How does it compare to Melanotan 1?
| Melanotan 1 | Melanotan 2 | |
|---|---|---|
| Tanning | Slower, lighter | Faster, darker |
| Timing | Morning | Evening |
| Other effects | Vitiligo, increased awareness | May stimulate erections |
| Selectivity | More selective | Less selective, hence the broader effects |
Melanotan 2 is less receptor-selective than Melanotan 1, which is why it produces effects beyond pigmentation. PT-141 was developed from Melanotan 2 specifically to isolate the sexual function effect.
Side effects
Generally minor: skin darkening, moles, freckles, nausea, vomiting, flushing, yawning. Effects fade after stopping use. Possible diarrhoea at higher doses.
Before you start: the mole question
Melanotan compounds darken existing moles and can cause new ones. Darkening and changing moles are also how melanoma presents, so a compound that changes every mole on your body makes the one that matters harder to spot.
- Get a skin check before starting, for a baseline
- Photograph existing moles
- Do not use with a personal or family history of melanoma without a dermatologist involved
- Any mole that changes shape, bleeds, or looks unlike the others needs assessment
Melanotan 2 in particular has case reports in the dermatology literature of melanoma diagnosed in users. That does not establish cause, and it is a reason for monitoring rather than avoidance.
Do your own research.
Sourcing and quality
Peptides sold outside compounding pharmacies are labelled "Not For Human Consumption and For Research Use Only." Always ask for batch-specific third-party testing.
VIGEO Health does not sell injectable peptides. Email dawn@vigeohealth.net.
What this page does not tell you
- Melanotan 2 is not approved anywhere, and unlike Melanotan 1 has no approved pharmaceutical counterpart.
- Nausea is common at higher doses, particularly during a jump start.
- Tanning is not sun protection.
- Skin monitoring is not optional.
- Long-term safety data does not exist.
Related
- Melanotan 1
- PT-141 — developed from Melanotan 2
- All peptides
Questions and Answers
Q: What is the difference between Melanotan 1 and Melanotan 2? A: Melanotan 2 tans faster and darker, is taken in the evening rather than the morning, and may also stimulate erections. It is less receptor-selective than Melanotan 1, which is why its effects extend beyond pigmentation. PT-141 was developed from Melanotan 2 to isolate the sexual function effect.