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DNA Mutations and Methylation Part 3


Let’s break down the DNA mutations a little further to see how each one can have an effect.  The five are called MTHFR, MTR, MTRR, AHCY, and COMT. We will start with MTHFR.  It is early in methylation cycle, and can affect all the other parts of the cycle if there is a lack of raw materials.

The MTHFR mutation is an inability to digest folic acid and convert to methylfolate.  Folic Acid is the most abundant nutrient in the human diet.    Much of our grain supply, flour, bread, pasta, cereal, rice and other processed foods are “enriched” or “fortified”.  Excess folic acid in people with this mutation causes the brain to run at twice the speed, while the body is left behind.

Symptoms of MTHFR mutation:  

1.       Generalized anxiety with no specific cause or trigger.  Probably noticeable on and off your whole life since about 1993.   Anti-anxiety medications don’t work, and make you feel like a zombie.

2.       Impaired intestinal motility, and inconsistent gut symptoms. 

3.       Intermittent gas, bloating, diarrhea, constipation, cramping, irritability, whether you have eaten recently or not.  

4.       Depression

5.       ADHD

6.       OCD

7.       Lay down exhausted, the body tired, and mind wakes up. 

8.       Allergies

Children and MTHFR:  Kids have never known a time when their food hasn’t been corrupted with folic acid. Kids who have trouble focusing or succeeding in school might be affected by a MTHFR mutation.  Try switching their sugary fortified cereals at breakfast for ham and eggs instead…within a week you may see huge, positive changes. 

What supplements might help?   

Methylfolate and other methylated B vitamins.  

Want to learn more about MTHFR?   This short podcast with Gary Brecka will give you an overview.

What about MTHFR and ADHD? 

MTHRF and Adrenal Fatigue:  


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